?
歐盟評估果糖硼酸鈣作為新型食品的安全性
2021-07-14 

歐盟評估果糖硼酸鈣作為新型食品的安全性

   食品伙伴網訊  2021年7月5日,據歐盟食品安全局(EFSA)消息,歐盟營養、新型食品和食物過敏源(NDA)研究小組就果糖硼酸鈣(calcium fructoborate)作為新型食品的安全性發表科學意見。

 

  經過評估,專家小組得出結論,在提議的用途和使用水平下,果糖硼酸鈣作為新型食品是安全的。部分原文報道如下:

 

  Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on calcium fructoborate as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF, produced by chemical synthesis, contains a maximum of 2.9% of boron and on average 4.7% calcium and 84.2% fructose. It is intended to be marketed as food supplements targeting the general adult population, excluding pregnant and lactating women, at a maximum level of 220 mg/day (maximum boron intake of 6.4 mg per day). The combined intake of boron from the background diet and the NF is in the range of 9.6–9.9 mg/day (corresponding to up to 0.14 mg/kg body weight (bw) per day given a default bw of 70 kg). This is in the range of the acceptable daily intake (ADI) of 0.16 mg/kg bw per day. Under conditions mimicking the gastrointestinal (GI) environment, the NF is fully hydrolysed and the Panel considered boron toxicity relevant for the safety assessment. The Panel considers that there is no concern with respect to genotoxicity of the NF. The effect induced by the NF in a 13-week rat study is consistent with toxicological findings induced by treatment with boron compounds in animal studies. Epididymides-to-brain weight ratio was identified as the most relevant endpoint and the reference point derived was the lowest model averaged BMDL10 value of 529 mg/kg bw per day. This corresponds to 14.8 mg/kg bw per day of boron, which is higher than the critical no observed adverse effect level (NOAEL) (9.6 mg boron/kg bw per day) used for establishing the ADI of 0.16 mg/kg bw per day for boron. The Panel therefore applied the present ADI for boron in the assessment of the NF. The Panel concludes that the NF, calcium fructoborate, is safe under the proposed uses and use levels.

 

  本文由食品伙伴網食品資訊中心編輯,供網友參考,有任何疑問,請聯系news@foodmate.net。

歐盟評估果糖硼酸鈣作為新型食品的安全性

健康生活交給食堂承包公司,讓您體驗休閑自在天地
XML地圖   HTML地圖   手機版
聯系電話:13539623688 徐先生
香草频视安卓下载-香草直播app下载大全-香草88app最新破解版